In gene therapy of adenosine deaminase (ADA) deficiency, the patient requires periodic…
Biology · NEET · NTA Exams — Biotechnology and its Applications
In gene therapy of adenosine deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because [NEET 2022]
- Lymphocytes from patient's blood are grown in culture, outside the body
- Genetically engineered lymphocytes are not immortal cells
- Retroviral vector is introduced into these lymphocytes
- Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages
Answer
(B) Genetically engineered lymphocytes are not immortal cells
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