Which of the following statements correctly differentiate(s) sickle-cell anaemia and…
Physics · NEET · NTA Exams — BASIC MATHEMATICS AND VECTOR
I. Sickle-cell anaemia is a qualitative defect in haemoglobin, while thalassemia is a quantitative defect.
II. Sickle-cell anaemia is caused by a point mutation, while thalassemia can be caused by gene deletion.
III. Thalassemia always involves the β-globin chain, while sickle-cell anaemia always involves the α-globin chain.
IV. Both disorders are autosome-linked recessive traits.
V. Sickle-cell anaemia results in elongated RBCs, while thalassemia results in microcytic RBCs.
Choose the correct answer from the options given below:
- I, II and III only
- I, III and IV only
- II, III and V only
- I, II, IV and V only
Answer
(D) I, II, IV and V only
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